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Viagra (Sildenafil citrate), which millions of men take for erectile dysfunction (ED), reduces the effects of hormonal stress on the heart by half, according to a study published online in the journal Circulation. Viagra causes genital blood vessels to expand, which helps in maintaining an erection. Recent research also has pointed to its potential usefulness in treating pulmonary hypertension. Prior to the latest findings by a team of Johns Hopkins researchers, it was thought to have little effect on the heart. Viagra, or sildenafil, blunts the strengthened heart beat caused by chemically induced stress, according to study senior author and cardiologist David Kass, MD, a professor at the Johns Hopkins University School of Medicine and its Heart Institute. It thereby lessens both the excess amount of blood and the force used to pump it to the body. "Sildenafil effectively puts a 'brake' on chemical stimulation of the heart," says Kass. Prevents and Reverses Effects of High BP These findings are believed to be the first confirmation in humans that Viagra has a direct effect on the heart. In earlier research, Kass and his team observed a similar effect in mice; Sildenafil blocked the short-term effects of hormonal stress in the heart. Related studies by the group show that sildenafil also prevents and reverses the long-term effects of chronic high blood pressure on the heart. Sildenafil reversed the negative effects on heart muscle weakened by heart failure and enlargement -- a condition called hypertrophy -- in mouse experiments Kass and his team carried out earlier this year. They reported their results in the journal Nature Medicine. "But we had no firm evidence as to whether or how this therapy might work in the human heart," says Kass. "Our latest research provides firm evidence this drug does indeed have an important impact on the heart." Increased Heartbeat Was Slowed Thirty-five healthy men and women, with an average age of 30 and no previous signs of coronary artery disease, participated in the six-month Johns Hopkins study. Within a three-hour timeframe, each participant received two separate injections of dobutamine (5 micrograms per kilogram for five minutes), a synthetic, adrenaline-like chemical that increases heart rate and pumping strength. Between injections, study participants were assigned randomly to a group that was treated with sildenafil (100 milligrams taken orally) or to a group given a sugar pill placebo. All participants then were given the second dobutamine injection to see what effects sildenafil or placebo had on the heart. Measurements of heart function were made before and after each injection. These included blood pressure readings, electrocardiograms and echocardiograms. Blood samples confirmed relatively equal levels of sildenafil and other enzymes. Each dobutamine injection stimulated heart function, increasing heart rate and the force of each heartbeat used to pump blood throughout the body, results showed. "This stimulation is similar to the way the nervous system normally increases heart function when triggered by emotional or exercise stress, or in diseases such as heart failure," notes Kass. After the first injection of dobutamine, the force of heart contraction increased by 150 percent in both groups. In the placebo group, this increase repeated itself after the second injection. However, in the group treated with sildenafil, the increased heartbeat was slowed by 50 percent, resulting in a smaller increase in blood flow and blood pressure generated by the heart in response to chemical stimulation. Between injections, heart function was not altered in the sildenafil group, demonstrating the absence of adverse side effects on the resting human heart. Stops PDE5A Action "Knowing more about the effects of sildenafil on heart function will allow for safer evaluation of its use as a treatment for heart problems," says Kass. "Our results set the stage for further studies of sildenafil's immediate and long-term effects on the heart and its ability to modify other neurohormonal and stress stimuli, including adrenaline and hypertension," he adds. While the precise biological actions of sildenafil in the heart are not fully understood, the drug is known to work by stopping the action of an enzyme, called phosphodiesterase 5 (PDE5A), Kass explains. This enzyme is involved in the breakdown of a key molecule, cyclic GMP, which helps control stresses and limit overgrowth in the heart. PDE5A is also the biological pathway that sildenafil blocks in the penis to prevent the relaxation of blood vessels and thus maintain erections. Copyright 2005 Daily News Central free penis enlarement pills medical penile enlargement herbal penis elargement pennis enlargement technique herbal natural penis enlagement vimax penis enlargement before and after photo vimax penis enlargment truth about penile enlargment pills

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The cause of premature ejaculation is not clear and the disease is believed to be mainly a psychological problem. To understand how premature ejaculation can be successfully treated, we need to present some facts related to ejaculation and its mechanism. The mechanism of ejaculation is actually quite complicated and is associated with three different simultaneous events: release of semen from the prostate (seminal emission), propelling the semen out the prostate and penis (ejaculation ), and prevention of semen going backwards into the bladder (bladder neck closure). In a very simple representation, the male ejaculatory mechanism consists of two reflexes: the glans-vasal and urethromuscular. Glans-vasal reflex seems to bring the semen to the posterior urethra (the emission phase of ejaculation) and then the urethromuscular reflex ejects it to the exterior (ejection phase of ejaculation). Deeply involved in mechanism of ejaculation is the paired, striated muscles at the base of the penis called the bulbospongiosus. Once the seminal fluid reaches the bulbous urethra, the bulbocavernosus muscle contraction (BCM) compresses the urethra and expelled its contents. This introduction was necessary because any dysfunction of all mentioned above seem to induce ejaculatory disorders and any treatment is close related to this dysfunction. Squeeze Technique aims to educate bulbocavernosus muscle to eliminate involuntary contractions that may cause the ejaculation with minimal sexual stimulation. This technique described by Masters and Johnson is very successful if the sufferer has a willing and understanding partner. The person with premature ejaculation is stimulated by his partner to the point of imminent ejaculation. Just prior to ejaculation, the partner squeezes the penis in its base to prevent ejaculation. Once the sensation of impending ejaculation has subsided, the process is repeated. Gradually, over time, a man can prolong his time until ejaculation. "Stop and start" method This involves sexual stimulation until the man recognizes that he is about to ejaculate. The stimulation is then removed for about thirty seconds and then may be resumed. The sequence is repeated until ejaculation is desired, the final time allowing the stimulation to continue until ejaculation occurs. To be successful this method also claims the partner co-operation. Reducing the stimulation For men with premature ejaculation a number of creams are available that can partially anesthetize (numb) the penis and reduce the stimulation that leads to orgasm. Another option is to use one or more condoms. However, either of these techniques may interfere with the pleasure experienced during sex. Drugs Alternatively, your doctor may prescribe medication that helps to delay ejaculation. Delayed orgasm is a common side effect of certain drugs, particularly those used to treat depression. When this type of medication is given to men who experience premature ejaculation, it can help to postpone orgasm for up to several minutes. manual penis enargement manual penile enlargment exercise does penis enargement work semenax vig rx safe penis elargement enhancement manhattan penis com enlargement pnis pnis pump penis enhancement program easy enlarement free penis surgery way

If someone uses viagra or any other drug used to treat erectile dysfunction (ED) then he must be getting alarmed by the price that he will pay for sexual satisfaction. I will not advice them that they should stop using viagra as a treatment but I would definitely suggest them to go for a cheaper choice that supplies the same result in the end. But let us first analyze what is the problem that makes a man use such medicines. It is erectile dysfunction. There are many things responsible for ED. It can be examined at different level that comprises psychology and medical reason. If a person is not sexually aroused even when he commits himself, it can be defined as erectile dysfunction. ED is constant inability of generating and maintaining erection hard enough to penetrate. It can occur at any age but ED loves to attack people in there fifties. Everyone faces an occasional stint of ED. As one grows old he can experience the change in erection function. It is natural and nothing to worry about because generic viagra has arrived to save men from getting embarrassed in bedroom. Pfizer introduced oral pill viagra in 1998 and it created uproar, which is contrary to the reaction generally related with a launch of any usual medication. Since then more then 23 million people have been put it to good use. Different pharmaceutical companies have launched generic version of viagra. It is just as safe and effective as their brand-name counterparts. Doctors worldwide are prescribing generic viagra to all those suffering from ED. The results have been encouraging and these men have enjoyed their sexual lives as before. Trials have shown that generic viagra is safe to use and can be combined with a number of medicines that one is prescribed or buys over the counter from time to time. There are many generic options of viagra available in most part of the world. Caverta, silagra, Edegra, kamagra, veega, and Meltabs are few trusted generic names used by ED patients. All these medicines and viagra have one thing in common and that is sildenafil citrate. The other common thing is that all these medicines are not effective until and unless a man is physically and mentally aroused by sex desire. Erectile dysfunction or impotence is an inability of a man to get or sustain an erection because of shortage of blood in penis. Doesn’t matter he is sexually stimulated or not. The causes of ED are different from person to person. As I said all these generic versions of viagra has a chemical called sildenafil citrate, which is the most important stuff, which helps arteries in the penis to relax and expand, by reducing the effect of an enzyme called pde5. Because of which more and more amount of blood flows into the penis resulting in hardness of penis and because of this hardness quantity of blood flowing out of the penis gets decreased and penis gets erected which last for long enough time to enjoy the sexual act. Just like viagra, generic viagra also does not provide protection from any sexually transmitted diseases, including HIV. These generic viagra medicines come in tablets of 25mg, 50mg, and 100mg. Most patients can start with 50mg. Generic versions of viagra can be taken 30 minutes before starting any sexually activity and the effect of all the generic versions of viagra lasts up to four to five hours just like viagra. There is no food restriction when it comes of using generic viagra, but there is a possibility that it may take a little longer to show its effect if it is taken after a high fat meals like fish, cheeseburger, french-fries etc. Just like viagra, generic viagra should not be taken more than once a day. Do not take more or less of it or take it more often than prescribed by your doctor. It is also advised to not to drink too much alcohol before taking generic viagra because drinking alcohol can cause a delay in getting erection. Just like viagra, generic viagra can cause some side effects. These effects are usually mild to moderate and usually don't last longer than a few hours. Some of these side effects are more likely to occur with higher doses. The most common side effects of generic viagra are headache, flushing of the face, and upset stomach. Less common side effects that may occur are temporary changes in color vision (such as trouble telling the difference between blue and green objects or having a blue color tinge to them), eyes being more sensitive to light, or blurred vision. In rare instances, men have complained of an erection that lasts many hours. This problem is called priapism. You should call a doctor immediately if you ever have an erection that lasts more than 4 hours. If not treated right away, permanent damage to your penis could occur. Heart attack, stroke, irregular heartbeats, and death have been reported rarely in men taking generic viagra. The best way to buy generic viagra is to go online pharmacy and order them. These Internet pharmacies sell cheap generic viagra as compared to other ways of buying medicines. Buying online, generic viagra gives the best prices along with free home delivery facility and complete caution. What more could one ask for from within the comforts of his sitting room. One thing I would like to remind is, always enjoy safe sex and for those who are suffering from ED, enjoy it with generic viagra. cheap vig rx vimax penis enlargement pump free penis enlagement pennis enlargement excersizes plus vig rx free penis enlargement best penis enlarement pills vimax penis enlargement pic before and after easy enlarement free penis surgery way

Having a baby brings with it many decisions. From the moment that second pink line appears you are a parent. Some parenting decisions can be fun, like what color to paint the nursery. Other decisions require more research and discussion between the mother and her partner including, if the child is a boy, whether or not to circumcise. The decision to circumcise may be guided by your religious beliefs. Both Jews and Muslims circumcise as part of religious rites. The decision not to circumcise, however, may be one that you never considered. “Aren’t most boys circumcised? Isn’t it cleaner? Why wouldn’t I want my son to look like his father and all the other boys in the locker room?” While these myths are prevalent in the United States and other parts of the Western world, the facts of circumcision tell a significantly different story. Circumcision of male infants is not a medically necessary procedure; it is plastic surgery for the penis. The practice of circumcision began in ancient Egypt, according to Desmond Morris in his book Babywatching. The ancient Egyptians believed that the snake shedding its skin was undergoing a rebirth and, thus, became immortal. They reasoned that if humans followed suit they, too, would attain immortality. The foreskin was equated to the snakeskin, and the practice of circumcision was begun. For centuries, the only reason for circumcision was a religious one. Non-faith based circumcision began with the Victorians during the mid-to-late 1800s. They believed that removing the foreskin would reduce the male’s urge to masturbate. From that starting point, circumcision has been deemed by various groups to be more hygienic and credited as a preventative measure for diseases from chlamydia to HIV. In reality, removing the foreskin accomplishes none of these assertions and could result in more serious problems. The foreskin has several known functions, even in modern times. While some people suggest that its use has gone the way of the appendix, in reality the foreskin aids in the sexual health and enjoyment of men. The foreskin is a protective cover for the penis that needs no special care. At birth, the foreskin is attached to the head of the penis, much like fingernails are attached to the end of your fingers. It will remain attached until the boy is about ten years old. Premature retraction of the foreskin can lead to an increased chance of infection. Early life functions of the foreskin are to help in the proper development of the penile glans and to protect the glans from feces and urine-based ammonia in diapers. Throughout the man’s life, the foreskin continues to protect the glans from friction and abrasion and keeps it lubricated and moisturized by coating it in a waxy, protective substance. When the man becomes sexually active, the foreskin allows sufficient skin to cover an erection by unfolding and aids in penetration by reducing friction and chafing. The foreskin is highly sensitive and is, in fact, an erogenous tissue rich with erogenous receptors. For his partner, the foreskin contacts and stimulates the female’s G-spot. There are additional considerations when deciding upon whether your male infant will undergo circumcision. As with any medical procedure, there are complications presented by the choice to circumcise. In March 1999, the American Academy of Pediatrics concluded that any potential medical benefits are not significant, and the AAP no longer recommends circumcision as a routine procedure. Prior to consenting to a circumcision, the mother must sign a consent form outlining the risks of the procedure. These risks include hemorrhage (in about 2% of cases), infection, deformity, scarring, permanent bowing of the penis (chordee), and urinary retention from swelling, among other concerns, including loss of the penis. Though rare, death occurs in approximately 1 of every 5000 circumcisions. Many circumcisions are done without the use of anesthetic, but if anesthesia is used, there are additional complications presented by using anesthetic drugs on an infant. Despite the American perception, circumcision is not a worldwide practice. Eighty-two percent (82%) of the world's male population is intact. That leaves the 18% of circumcised men in the minority. Even in the U.S. circumcision rates are declining. Starting around World War II, rates of circumcised boys increased steeply as American births were moved from the home into the hospitals. Rates of U.S. circumcisions reached a plateau during the late 1980s. With the new century, rates of circumcision began a slow decline. In the latest census reports, from 2003, approximately 55% of American newborn boys are circumcised. Some sources believe that American circumcision rates will decrease steadily over the next generation and return to the pre-WWII ratio of approximately 1 of every 4 boys being circumcised. Whether or not to circumcise is a decision that must be made with concern for immediate and future implications for the male child. As more parents become aware of the choices they have in labor and birth, more parents are also making the decision not to circumcise. For more information on circumcision, visit www.nocirc.org. penile enlargment before and after picture home penis enargement penis enlarement pills penis elargement forum magna rx results penis enlagement information natural penile enlargement exercise natural penis enlargment exercise easy enlarement free penis surgery way

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